LOCALLY ACTING DRUGS ON SKIN AND MUCOUS MEMBRANES

1. Demulcents

Gum Acacia

Gum Tragacanth

Glycyrrhiza

Methylcellulose

Propylene glycol

Glycerine

 

2. Emollients

a. Vegetable oils:

Olive oil

Arachis oil

Sesame oil

Cocoa butter

b. Animal products:

Wool fat

Lard

Bees wax

Spermaceti

c. Petroleum products:

Paraffin wax (soft/hard)

Liquid paraffin

 

3. Adsorbants and Protectives

a. Dermal protectives:

Magnesium stearate

Zinc stearate

Talc

Calamine

Zinc oxide,

Bentonite

Starch

Boric acid

Aloe-vera gel

b. Occlusive protectives:

Polyvinyl polymer

Feracrylum

Dimethicone

Sucralfate

 

4. Astringents

a. Vegetable astringents:

Tannic acid: as glycerine of tannic acid 25%

Tannins: as tincture catechu, tea leaf infusion

b. Alcohols:

Ethanol

Methanol

Propanol

c. Mineral astringents:

Alum

Aluminium hydroxychloride

Zinc oxide

Zirconyl hydroxychloride

 

5. Counterirritants

a. Volatile  oils:

Turpentine oil

Eucalyptus oil

Clove oil

b. Stearoptenes:

Camphor

Thymol

Menthol

c. Other counterirritants:

Mustard seeds (as mustard plaster)

Capsicum

Canthridin

Methylsalicylate

Alcohol

 

6. Keratolytics and Caustics

Salicylic acid

Resorcinol

Podophyllum resin

Silver nitrate

Phenol

Trichloracetic acid

Glacial acetic acid

 

7. Antiseborrheics

 

Selenium sulphide

Zinc pyrithione

Sulfur

Resorcinol

Coal tar

Ketoconazole

Clotrimazole

Topical cortico-steroids

 

8. Melanizing agents

 

Psoralen

Methoxsalen

Trioxsalen

 

9. Demelanizing agents

Hydroquinone

Monobenzone

Azelaic acid

 

10. Sunscreens

a. Chemical sunscreens:

Para-aminobenzoic acid (PABA)

Oxybenzone

Octyl methoxy cinnamate

b. Physical sunscreens:

Petroleum jelly (heavy)

Titanium dioxide

Zinc oxide

Calamine

 

11. Drugs for Psoriasis

Topical corticosteroids

Calcipotriol

Tazarotene

Coaltar

Acitretin

Psoralen-ultraviolet A (PUVA) therapy

    Immunosuppressants:

Methotrexate

Etanercept

 

12. Drugs for Acne vulgaris

a. Topical therapy:

Antimicrobials:

Benzoyl peroxide

Erythromycin

Clindamycin

Nadifloxacin

Retinoids:

Tretinoin (Retinoic acid, all trans vitamin A acid)

Adapalene

Tazarotene

Others:

Azelaic acid

 

b. Systemic therapy:

Antibiotics:

Tetracycline

Minocycline

Erythromycin

Retinoid:

Isotretinoin (13-cis retinoic acid)

 

 

 

LOCALLY ACTING DRUGS ON SKIN AND MUCOUS MEMBRANES
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